Energy-Based Systematic Modeling of Adaptive Immune Repertoire Behavior: Study on Cell Proliferation & Somatic Hypermutation process
Yexing Chen, Haiwen Ni, Yongjie Li, Jin Ma, Chen-Tsung Huang, Sixian Yang, Xiangfei Xie, Haitao Lv, Min Li, Peng Cao
This study develops a mathematical model to describe immune repertoire dynamics, including cell proliferation and somatic hypermutation, validated using mouse spleen and human PBMC data.
Fundamental Research · Jun 3, 2025Peer-reviewedBioinformatics