Bacterial diadenylate cyclase domains synthesize diverse nucleotide signals in anti-phage defense
Adelyn E. Ragucci, Danielle J. Haley, Philip J. Kranzusch
The paper identifies a bacterial anti-phage defense system called Panoptoo, which uses DAC enzymes to synthesize nucleotide signals that counteract phage immune evasion.
bioRxiv · Aug 11, 2026 · PreprintMicrobiology