NeurosciencebioRxivPreprint
Loss of TDP-43 induces synaptic dysfunction that is rescued by UNC13A splice-switching ASOs
Matthew J. Keuss, Peter Harley, Eugeni M. Ryadnov…·Pietro Fratta
This study shows that loss of TDP-43 causes synaptic dysfunction through a cryptic exon in UNC13A, which is rescued by antisense oligonucleotides.
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