Cancer BiologyFrontiers in OncologyPeer-reviewed
A structure-based tool to interpret the significance of kinase mutations in clinical next generation sequencing in cancer
Amith Vikram Rangarajan, Ilona Sviezhentseva, Emma L. Gunderson…·Beth Apsel Winger
The paper develops a structure-based tool to evaluate kinase mutations in cancer by aligning them with known activating mutations using structural and functional data.
DOI 10.3389/fonc.2025.1599389