ImmunologybioRxivPreprint
IL-1RA Disrupts ATP Activation of P2RX7 in Human Monocyte-Derived Microglia-like Cells
Kelsey S. Heavener, Khushbu Kabra, Maedot Yidenk, Elizabeth M. Bradshaw
This study shows that P2RX7 in human microglia-like cells mediates ATP-induced cytokine production and amyloid-beta uptake, and its function is modulated by IL-1 signaling.
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