Prevention of tau accumulation through inhibition of hnRNP R-dependent axonal Mapt mRNA localization
Abdolhossein Zare, Saeede Salehi, Michael Briese, Michael Sendtner
This study shows that inhibiting hnRNP R reduces axonal tau levels and tau tangles in Alzheimer's disease mice, suggesting a targeted therapeutic approach.
bioRxiv · Jul 19, 2023 · PreprintNeuroscience