Michael Briese

The paper investigates how CASPR2 autoantibody subclasses, particularly IgG4, affect neuronal excitability and potassium channel function in patients with neuropathic pain.

The paper isolates nerve terminals from NaV1.9 knockout mice and performs proteomic analysis to identify dysregulated pathways in neuropathic pain signaling.

This study shows that inhibiting hnRNP R reduces axonal tau levels and tau tangles in Alzheimer's disease mice, suggesting a targeted therapeutic approach.

This study investigates stage-dependent molecular and cellular changes in a rat model of hypertension, revealing vascular and neural pathways linked to inflammation and cognitive dysfunction.

The paper uses spliceosome iCLIP to map human spliceosome engagement with snRNAs and pre-mRNAs, identifying over 50,000 branchpoints and their associated splicing factor binding patterns.