Olof Hellgren

Parasite epigenetic memory and blood barriers dictate host transcriptional responses during generalist host-shifts

This study shows that parasite epigenetic memory and blood barriers influence host transcriptional responses during host shifts, revealing distinct immune and metabolic responses to homologous vs. heterologous infections.

The genome of the avian malaria parasite Haemoproteus majoris (lineage WW2) and its relationship to other Plasmodium species

The paper presents the first assembled genome of Haemoproteus majoris, a common avian malaria parasite, and discusses its genomic features and evolutionary significance.

Spatiotemporal and demographic effects on avian malaria prevalence in blue tits

The paper investigates how host age, sex, and location affect avian malaria prevalence in blue tits over time, finding age-related accumulation of infections and sex-specific differences in Leucocytozoon prevalence.

Climate-driven increase in transmission of wildlife malaria parasite over the last quarter century

The study shows climate warming has increased malaria parasite prevalence and transmission in blue tits over 26 years, with specific temperature windows driving the trend.

Generalist malaria parasites and host imprinting: Unveiling transcriptional memory

This study investigates how the avian malaria parasite P. homocircumflexum adjusts its gene expression across different bird hosts, finding evidence for epigenetic inheritance and transcriptional plasticity.

Beyond immunity: a transcriptomic landscape of Plasmodium's modulation of mosquito metabolic pathways

This study examines how Plasmodium modulates mosquito metabolic pathways through transcriptomic analysis, revealing potential parasite-driven manipulation of host physiology.