Dongheon Lee

Keystone engineering enables collective range expansion in microbial communities

The paper shows keystone engineering enables microbial range expansion by antibiotic-degrading bacteria, revealing spatial effects in microbial communities.

A foundation model for microbial growth dynamics

This paper develops a foundation model for microbial growth dynamics using self-supervised learning on diverse datasets, enabling accurate reconstruction and prediction of growth patterns and antibiotic responses.

Transposon-plasmid nesting enables fast response to fluctuating environments

The paper shows transposon-plasmid nesting allows microbes to rapidly respond to environmental changes by combining genetic mobility with copy number amplification.