Author

Gemma Comes

Universitat Autònoma de BarcelonaORCID 0000-0002-4074-7665Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Carla CanaliD· 1 shared Elisenda SanziD· 1 shared Juan HidalgoiD· 1 shared Kevin AguilariD· 1 shared Mercedes GiraltiD· 1 shared Paula SanchísiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperNeuroscience

Carla CanalORCID

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1 paper

Recent·Most cited

Chronic central-targeted Interleukin-6 overexpression promotes hippocampal and cortical neuropathology in the Tg2576 mouse model of Alzheimer's disease

Carla Canal, Kevin Aguilar, Gemma Comes, Elisenda Sanz, Mercedes Giralt, Paula Sanchís, Juan Hidalgo

This study shows that chronic central IL-6 overexpression in Tg2576 mice worsens amyloidosis-related neuropathology and alters cortical and hippocampal gene expression, with sex-dependent effects.

Alzheimer s Research & Therapy · Jun 9, 2026Peer-reviewedNeuroscience