Molecular BiologybioRxivPreprint
Natural Product-Like Fragments Unlock Novel Chemotypes for a Kinase Target - Exploring Options beyond the Flatland
Anna Santura, Janis Müller, M. Wolter…·Paul Czodrowski
This study screens a natural product-like fragment library against PKA, identifies novel binders with unique chemical properties, and highlights their potential for improved selectivity and clinical success.