Author

Antonella Castellano

Vita-Salute San Raffaele UniversityORCID 0000-0002-4137-9016Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:imaging· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

Andrea FaliniiD· 2 shared Daniele DiniiD· 2 shared Ferdinando Rodriguez y BaenaiD· 2 shared Lorenzo BelloiD· 2 shared Marco RivaiD· 2 shared Nicolò PeccoiD· 2 shared Riccardo SecoliiD· 2 shared Stefano GalvaniD· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Andrea FaliniORCID

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2 papers

Recent·Most cited

In vivo MRI measurement of microstructural constraints for direct delivery of therapeutics within the brain

Antonella Castellano, Valentina Pieri, Alice Segato, Marco Riva, Nicolò Pecco, Yuan Tian, Marco Vidotto, Davide Danilo Zani, Stefano Brizzola, Marco Trovatelli, Giuliano Ravasio, Riccardo Secoli, Stefano Galvan, Daniele Dini, Lorenzo Bello, , Andrea Falini

This study uses in vivo MRI to assess how brain microstructure affects therapeutic delivery via convection-enhanced delivery in an ovine model.

bioRxiv · Apr 15, 2025 · PreprintNeuroscience

Decoding Brain Interstitial Transport In Vivo: A Fully Validated Bottom-Up Mechanistic Prediction Framework

Yuan Tian, Nicolò Pecco, Wenbo Zhan, Stefano Galvan, Riccardo Secoli, Marco Riva, Lorenzo Bello, Andrea Falini, Ferdinando Rodriguez y Baena, Antonella Castellano, Daniele Dini

This paper develops a validated mechanistic framework to predict brain interstitial transport in vivo using mathematical modeling, imaging, and biomechanical testing, demonstrating its application in sheep brains.

bioRxiv · Mar 22, 2025 · PreprintBiophysics