Daniele Dini

This study develops a 3D computational framework to model cerebral haemodynamics, arterial wall deformation, and brain tissue motion, benchmarked against in vivo measurements.

This study identifies sequence-dependent rules for collagen contraction driven by water-mediated structural rearrangements during dehydration.

This study uses in vivo MRI to assess how brain microstructure affects therapeutic delivery via convection-enhanced delivery in an ovine model.

This paper develops a validated mechanistic framework to predict brain interstitial transport in vivo using mathematical modeling, imaging, and biomechanical testing, demonstrating its application in sheep brains.