Author

Craig J. Newschaffer

Pennsylvania State UniversityORCID 0000-0002-4148-3593Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 5 Approach:statistical model· 5 Research Focus:differential expression· 4 Assay:DNA methylation· 4 Research Focus:gene regulatory network inference· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Lisa CroeniD· 5 shared M. Daniele FalliniD· 5 shared Christine Ladd‐AcostaiD· 4 shared Irva Hertz‐PicciottoiD· 4 shared Kelly M. BakulskiiD· 4 shared Andrew P. FeinbergiD· 3 shared Shan V. AndrewsiD· 3 shared Brooke K. SheppardiD· 2 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersGenomics

Lisa CroenORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Placenta DNA methylation at ZNF300 is associated with fetal sex and placental morphology

Christine Ladd‐Acosta, Shan V. Andrews, Kelly M. Bakulski, Jason I. Feinberg, Rakel Tryggvadóttir, Ruofan Yao, Lisa Croen, Irva Hertz‐Picciotto, Craig J. Newschaffer, Carolyn M. Salafia, Andrew P. Feinberg, Kasper D. Hansen, M. Daniele Fallin

The paper identifies DNA methylation at ZNF300 associated with fetal sex and placental morphology using whole genome bisulfite sequencing and multiple datasets.

bioRxiv · Mar 5, 2021 · PreprintGenomics

Cord blood DNA methylome in newborns later diagnosed with autism spectrum disorder reflects early dysregulation of neurodevelopmental and X-linked genes

Charles E. Mordaunt, Julia M. Jianu, Benjamin I. Laufer, Yihui Zhu, Hyeyeon Hwang, Keith W. Dunaway, Kelly M. Bakulski, Jason I. Feinberg, Heather E. Volk, Kristen Lyall, Lisa Croen, Craig J. Newschaffer, Sally J. Ozonoff, Irva Hertz‐Picciotto, M. Daniele Fallin, , Janine M. LaSalle

The paper identifies DNA methylation differences in cord blood samples from newborns later diagnosed with ASD, revealing sex-specific epigenomic signatures linked to neurodevelopmental and X-linked genes.

Genome Medicine · Oct 14, 2020Peer-reviewedGenomics

A meta-analysis of two high-risk prospective cohort studies reveals autism-specific transcriptional changes to chromatin, autoimmune, and environmental response genes in umbilical cord blood

Charles E. Mordaunt, Bo Young Park, Kelly M. Bakulski, Jason I. Feinberg, Lisa Croen, Christine Ladd‐Acosta, Craig J. Newschaffer, Heather E. Volk, Sally J. Ozonoff, Irva Hertz‐Picciotto, Janine M. LaSalle, Rebecca J. Schmidt, M. Daniele Fallin

This study identifies ASD-specific transcriptional changes in umbilical cord blood through a meta-analysis of two high-risk cohorts, highlighting environmental, immune, and epigenetic factors.

Molecular Autism · Oct 24, 2019Peer-reviewedGenomics

Peripheral blood DNA methylation and autism spectrum disorder

Shan V. Andrews, Brooke K. Sheppard, Gayle C. Windham, Laura A. Schieve, Diana Schendel, Lisa Croen, Pankaj Chopra, Reid S. Alisch, Craig J. Newschaffer, Stephen T. Warren, Andrew P. Feinberg, M. Daniele Fallin, Christine Ladd‐Acosta

This paper presents the largest case-control epigenome-wide association study (EWAS) for autism spectrum disorder (ASD) using blood DNA methylation data, finding no significant CpG sites but suggestive associations and concordance with brain samples.

Molecular Autism · Jun 28, 2018Peer-reviewedGenomics

Cross-tissue integration of genetic and epigenetic data offers insight into autism spectrum disorder

Shan V. Andrews, Shannon Ellis, Kelly M. Bakulski, Brooke K. Sheppard, Lisa Croen, Irva Hertz‐Picciotto, Craig J. Newschaffer, Andrew P. Feinberg, Dan E. Arking, Christine Ladd‐Acosta, M. Daniele Fallin

The paper integrates genetic and epigenetic data to identify ASD-associated SNPs enriched in tissue-specific meQTLs and reveals immune-related pathways and psychiatric condition links.

Nature Communications · Oct 12, 2017Peer-reviewedGenomics