The paper tracks the adoption of bioimage-analysis software across 1.7 million microscopy papers from 2010 to 2025, finding increased usage and concentration on general-purpose platforms like ImageJ/Fiji.

bioRxiv · Nov 1, 2026 · PreprintBioinformatics

VLab4Mic: prediction of structural resolvability in super-resolution microscopy

Damián Martínez, Bruno M. Saraiva, Tayla Shakespeare, Mark Bates, Dylan M. Owen, Christophe Leterrier, Mario Del Rosario, Ricardo Henriques

VLab4Mic predicts structural resolvability in super-resolution microscopy by simulating imaging configurations and comparing results to experimental data.

bioRxiv · Jul 9, 2026 · PreprintBioinformatics

Mapping EGFR1 sorting domains in endosomes with a calibrated 3D expansion microscopy toolkit

Tayla Shakespeare, Rajpinder S. Seehra, Neftali Flores Rodriguez, Nkolika Atuanya, Thomas M. D. Sheard, Ralf Köhler, Daniel A. Bose, Philip G. Woodman, Barbara Ciani, Izzy Jayasinghe

This paper develops a 3D expansion microscopy toolkit to visualize and quantify nanoscale interactions in endosomes, revealing EGF and EGFR1 enrichment and Rab5a accumulation during endosomal maturation.

bioRxiv · Oct 1, 2025 · PreprintBiophysics