Heterogeneous T cell responses across Hepatitis B virus clinical phases revealed by rapid whole-blood HBV T cell analysis
Nina Le Bert, Apostolos Koffas, Rajneesh Kumar, F. Facchetti, Anthony Tanoto Tan, Upkar S. Gill, Lung‐Yi Mak, Sophie Stretch, Tizong Miao, Smrithi Hariharaputran, Shou Kit Hang, Yifei Guo, Qi Chen, Elisabetta Degasperi, Pietro Lampertico, , Patrick T.F. Kennedy
This study introduces HBV-CRA, a rapid whole-blood assay that identifies immune profiles associated with HBsAg clearance and reveals heterogeneous T cell responses in chronic hepatitis B patients.
bioRxiv · Feb 11, 2025 · PreprintImmunology