Guruduth S. Banavar

Metatranscriptomics-Derived Disease Risk Scores as a Preventive, Diagnostic, and Treatment Support Tool

The paper develops and validates a Disease Risk Score (DRS) framework using metatranscriptomics data to assess disease risk, showing significant risk enrichment for 15 diseases in an independent cohort.

The human gut microbiome activity is resilient and stable for up to six months: a large stool metatranscriptomic study

This study shows the human gut microbiome remains stable in composition and function for up to six months, with resilience to short-term disruptions like colonoscopy preparation.

Preparation of robust Synthetic Control samples and their use in a metatranscriptomic clinical test

The paper develops synthetic control samples for metatranscriptomic diagnostics, validated in a clinical lab with high reproducibility and signal strength.

Microbial functional pathways based on metatranscriptomic profiling enable effective saliva-based health assessments for precision wellness

The paper develops microbial functional pathway scores from metatranscriptomic data to assess oral health and disease phenotypes using saliva samples.

Data-driven precision nutrition improves clinical outcomes and risk scores for IBS, depression, anxiety, and T2D

This paper presents a data-driven precision nutrition platform that improves clinical outcomes and risk scores for IBS, depression, anxiety, and T2D through personalized dietary recommendations based on gut microbiome and host gene expression data.

Gut microbiome activity contributes to individual variation in glycemic response in adults

The paper shows gut microbiome activity predicts individual glycemic responses to meals, beyond diet and body metrics.

An accurate aging clock developed from the largest dataset of microbial and human gene expression reveals molecular mechanisms of aging

This paper develops an aging clock using human and microbial gene expression data, showing associations between biological age and lifestyle factors.

A clinically validated human capillary blood transcriptome test for global systems biology studies

The paper develops a clinically validated transcriptome test using capillary blood for global systems biology studies, enabling affordable and accessible gene expression analysis.

A robust metatranscriptomic technology for population-scale studies of diet, gut microbiome, and human health

Viomega is a robust, automated stool metatranscriptomic method for population-scale studies, demonstrating stability and consistency across 10,000 samples.