Author

Silvia Vega-Rubín-de-Celis

Essen University HospitalORCID 0000-0002-4196-8996Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:clinical cohort / trial· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Feng SheniD· 1 shared Hao SheniD· 1 shared Jiahong Wang· 1 shared Jieru Huang· 1 shared Josephine W. ThinwaiD· 1 shared Qisheng Zhang· 1 shared Runya Fang· 1 shared Tao YuaniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Feng ShenORCID

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1 paper

Recent·Most cited

Ligand-independent c-Met activation by HHLA2 drives hepatocellular carcinoma and predicts c-MET inhibitor efficacy

Xubo Huang, Runya Fang, Yuqian Pang, Zhe Zhang, Jieru Huang, Yuting Li, Tao Yuan, Yun Zeng, Zhao Yao, Silvia Vega-Rubín-de-Celis, Josephine W. Thinwa, Qisheng Zhang, Hao Shen, Jiahong Wang, Feng Shen, Yongjie Wei

This study identifies HHLA2 as a ligand-independent activator of c-Met in HCC, showing its role in tumor progression and its predictive value for c-Met inhibitor response.

Journal of Experimental & Clinical Cancer Research · May 20, 2025Peer-reviewedCancer Biology