Single-cell analyses reveal that monocyte gene expression profiles influence HIV-1 reservoir size in acutely treated cohorts
Philip K. Ehrenberg, Aviva Geretz, Meta Volčič, Taisuke Izumi, Lauren K. Yum, Adam Tully Waickman, Shida Shangguan, Dominic Paquin‐Proulx, Matthew Creegan, Meera Bose, Kawthar Machmach, Aidan McGraw, Akshara Narahari, Jeffrey R. Currier, Carlo Sacdalan, , Rasmi Thomas
The paper uses scRNA-seq to show that monocyte IL1B expression inversely correlates with HIV-1 reservoir size in ART-treated individuals.
Nature Communications · May 29, 2025Peer-reviewedImmunology