Author

Tomohiro Kikuchi

Jichi Medical UniversityORCID 0000-0002-4222-4569Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Organism:non-human primate· 1

Frequent Co-Authors

Akihiro Kume· 1 shared Atsushi Ugajin· 1 shared Harushi MoriiD· 1 shared Hitoyasu Nakamura· 1 shared Kazuhiro EndoiD· 1 shared Morisada HayakawaiD· 1 shared Naohiro SataiD· 1 shared Nemekhbayar BaatartsogtiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Akihiro Kume

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1 paper

Recent·Most cited

Efficient Gene Transduction in Pigs and Macaques with the Engineered AAV Vector AAV.GT5 for Hemophilia B Gene Therapy

Yuji Kashiwakura, Kazuhiro Endo, Atsushi Ugajin, Tomohiro Kikuchi, Shuji Hishikawa, Hitoyasu Nakamura, Yuko Katakai, Nemekhbayar Baatartsogt, Takafumi Hiramoto, Morisada Hayakawa, Nobuhiko Kamoshita, Shoji Yamazaki, Akihiro Kume, Harushi Mori, Naohiro Sata, , Tsukasa Ohmori

This study evaluates the efficacy and immunogenicity of the AAV.GT5 vector for hemophilia B gene therapy in pigs and macaques, finding improved transduction and reduced immunogenicity compared to AAV-Spark100.

Molecular Therapy — Methods & Clinical Development · Aug 22, 2023Peer-reviewedGenetics