Author

Yuko Katakai

Corporation for Production and Research of Laboratory Primates

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Organism:non-human primate· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:protein sequence· 1

Frequent Co-Authors

Morisada HayakawaiD· 2 shared Nemekhbayar BaatartsogtiD· 2 shared Tsukasa OhmoriiD· 2 shared Yuji KashiwakuraiD· 2 shared Akihiro Kume· 1 shared Akiyo Kawanobe· 1 shared Atsushi Ugajin· 1 shared Eiko Nakano MinakawaiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBioengineering

Morisada HayakawaORCID

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Author profile →

3 papers

Recent·Most cited

Engineered coagulation factor VIII with enhanced secretion and coagulation potential for hemophilia A gene therapy

Yuji Kashiwakura, Yuto Nakajima, Kio Horinaka, Tiago J. S. Lopes, Yuma Furuta, Yuki Yamaguchi, Nemekhbayar Baatartsogt, Morisada Hayakawa, Yuko Katakai, Susumu Uchiyama, Osamu Nureki, Keiji Nogami, Tsukasa Ohmori

This paper develops engineered FVIII variants for hemophilia A gene therapy, showing improved secretion, coagulation activity, and efficacy at lower vector doses in mice and macaques.

Blood · Nov 7, 2025Peer-reviewedBioengineering

Establishment of a second-generation transgenic marmoset model of polyglutamine disease recapitulating neurological symptoms and pathology

Eiko Nakano Minakawa, Kensuke Owari, Naotake Nogami, Terumi Nakatani, Masashi Koizumi, Akiyo Kawanobe, Yosuke Saga, Moeko Kudo, S. Noguchi, Takashi Hanakawa, Yuki Hori, Hidemi Numazawa, Toshihide Takeuchi, Yuko Katakai, Ryoichi Saito, , Kazuhiko Seki

This paper describes a second-generation transgenic marmoset model of SCA3 that replicates motor impairments and neuropathology, offering a platform for studying disease mechanisms and therapies.

bioRxiv · Mar 12, 2025 · PreprintNeuroscience

Efficient Gene Transduction in Pigs and Macaques with the Engineered AAV Vector AAV.GT5 for Hemophilia B Gene Therapy

Yuji Kashiwakura, Kazuhiro Endo, Atsushi Ugajin, Tomohiro Kikuchi, Shuji Hishikawa, Hitoyasu Nakamura, Yuko Katakai, Nemekhbayar Baatartsogt, Takafumi Hiramoto, Morisada Hayakawa, Nobuhiko Kamoshita, Shoji Yamazaki, Akihiro Kume, Harushi Mori, Naohiro Sata, , Tsukasa Ohmori

This study evaluates the efficacy and immunogenicity of the AAV.GT5 vector for hemophilia B gene therapy in pigs and macaques, finding improved transduction and reduced immunogenicity compared to AAV-Spark100.

Molecular Therapy — Methods & Clinical Development · Aug 22, 2023Peer-reviewedGenetics