Splicing inactivation generates hybrid mRNA-snoRNA transcripts targeted by cytoplasmic RNA decay
Yanru Liu, Samuel DeMario, Kevin L. He, Michelle R. Gibbs, Keaton Barr, Guillaume Chanfreau
The paper shows that splicing inactivation leads to hybrid mRNA-snoRNA transcripts that are degraded by cytoplasmic decay, highlighting splicing's role in snoRNA biogenesis.
Proceedings of the National Academy of Sciences · Jul 25, 2022Peer-reviewedMolecular Biology