Kevin L. He

The paper shows that transcription termination defects in yeast lead to splicing inefficiency and errors, highlighting its importance for splicing fidelity in compact genomes.

This study investigates the role of zinc finger domains in the yeast splicing factor Luc7 using humanized variants, revealing their impact on splice site selection and interactions with Prp28.

NanoBlot visualizes RNA isoform usage from third-generation sequencing data by generating Northern blot and RT-PCR-like images, offering customization and multiplexing capabilities.

The paper shows that splicing inactivation leads to hybrid mRNA-snoRNA transcripts that are degraded by cytoplasmic decay, highlighting splicing's role in snoRNA biogenesis.

This study experimentally shows that Per2AS regulates circadian clock amplitude through a negative feedback loop with Per2, without producing a protein.