Qilai Huang

Protein inverse folding through joint modeling of surface and backbone geometry

This paper introduces Surleton, a framework for inverse protein folding that jointly models backbone and surface geometry, improving sequence recovery and predictive confidence on benchmark datasets.

VSTM2L protects prostate cancer cells against ferroptosis via inhibiting VDAC1 oligomerization and maintaining mitochondria homeostasis

A dinucleotide tag-based parallel reporter gene assay method

This paper introduces a dinucleotide-tag reporter system (DiR) to assess regulatory elements with reduced bias, demonstrating its application in evaluating prostate cancer risk SNPs.