Phase separation of protein kinase A regulatory subunits is driven by similar inter- and intra-molecular interactions involving the inhibitory segment
Malyasree Giri, Christopher Brasnett, Kubra F. Eroglu, Julie Maibøll Buhl, Alain A.M. André, Siewert J. Marrink, Frans A. A. Mulder, Magnus Kjærgaard
This study investigates the phase separation of PKA RI regulatory subunits using NMR and MD simulations, revealing similar inter- and intra-molecular interactions driving this process.
bioRxiv · Aug 7, 2025 · PreprintBiophysics