Author

Evdokia Paza

UK Dementia Research InstituteORCID 0000-0002-4297-8598Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Bhuvaneish Thangaraj SelvarajiD· 2 shared David StoryiD· 2 shared James D. CooperiD· 2 shared Josef PrilleriD· 2 shared Karen Burr· 2 shared Poulomi BanerjeeiD· 2 shared Siddharthan ChandraniD· 2 shared Alessandra Cardinalli· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersNeuroscience

Bhuvaneish Thangaraj SelvarajORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJun 24, 2024

Human induced pluripotent stem cell-derived microglia contribute to thepathophysiology of Fragile X syndrome via increased RAC1 signaling

Poulomi Banerjee, Shreya Das Sharma, Karen Burr…·Siddharthan Chandran

This study shows that FMRP loss in microglia increases RAC1 signaling, leading to inflammation and neuronal hyperexcitability in FXS, which can be mitigated by RAC1 inhibition.

DOI 10.1101/2024.06.24.600387

humanbulk RNA-seq

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NeuroscienceScience AdvancesPeer-reviewedApr 21, 2023

Cell-autonomous immune dysfunction driven by disrupted autophagy in C9orf72-ALS iPSC-derived microglia contributes to neurodegeneration

Poulomi Banerjee, Arpan R. Mehta, Raja Sekhar Nirujogi…·Siddharthan Chandran

This study shows that C9orf72 mutations disrupt autophagy in microglia, leading to immune dysfunction and increased motor neuron death in ALS/FTD.

54 citationstop 1%

humanexperimental assay

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