Author

Shreya Das Sharma

UK Dementia Research InstituteORCID 0009-0008-7536-4542Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Sumantra ChattarjiiD· 2 shared Aditi BhattacharyaiD· 1 shared Alessandra Cardinalli· 1 shared Bhuvaneish Thangaraj SelvarajiD· 1 shared David StoryiD· 1 shared Evdokia PazaiD· 1 shared James D. CooperiD· 1 shared Josef PrilleriD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersNeuroscience

Sumantra ChattarjiORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJun 24, 2024

Human induced pluripotent stem cell-derived microglia contribute to thepathophysiology of Fragile X syndrome via increased RAC1 signaling

Poulomi Banerjee, Shreya Das Sharma, Karen Burr…·Siddharthan Chandran

This study shows that FMRP loss in microglia increases RAC1 signaling, leading to inflammation and neuronal hyperexcitability in FXS, which can be mitigated by RAC1 inhibition.

DOI 10.1101/2024.06.24.600387

humanbulk RNA-seq

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NeuroscienceEMBO ReportsPeer-reviewedApr 29, 2020

Distinct Regulation of Bioenergetics and Translation by Gp I mGluR and NMDAR

Sudhriti Ghosh Dastidar, Shreya Das Sharma, Sumita Chakraborty…·Ravi Sondekoppa Muddashetty

The paper shows that mGluR and NMDAR regulate protein synthesis and ATP consumption in cortical neurons through distinct kinetics and AMPK-eEF2 signaling.

16 citations

mouseproteomics

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