Author

Kristin Wallace

Medical University of South CarolinaORCID 0000-0002-4297-9064Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Organism:human· 2 Assay:imaging· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Assay:metagenomics· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Alexander V. AlekseyenkoiD· 3 shared Elizabeth C. O’QuinniD· 2 shared Souvik SealiD· 2 shared Anand S. MehtaiD· 1 shared Antonis KourtidisiD· 1 shared Bashir ‎HamidiiD· 1 shared Brian NeeloniD· 1 shared Chenthamarakshan VasuiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersBioinformatics

Alexander V. AlekseyenkoORCID

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Author profile →

3 papers

Recent·Most cited

Differences in T-cell counts and neighborhood patterns in human colorectal adenomas and sessile serrated lesions

Souvik Seal, Lauren Rose Fanning, Evan M. Bagley, Christine E. Bookhout, Elizabeth L. Barry, Elizabeth C. O’Quinn, Dale C. Snover, David Lewin, Silvia Guglietta, Antonis Kourtidis, Martha J. Shrubsole, John A. Baron, Todd A. MacKenzie, Alexander V. Alekseyenko, Kristin Wallace

The paper compares T-cell counts and spatial patterns in colorectal adenomas and sessile serrated lesions, finding differences in T-cell infiltration and clustering by lesion type.

bioRxiv · Jan 6, 2026 · PreprintPathology

SpaceANOVA: Spatial co-occurrence analysis of cell types in multiplex imaging data using point process and functional ANOVA

Souvik Seal, Brian Neelon, Peggi M. Angel, Elizabeth C. O’Quinn, Elizabeth Goodwin Hill, Thao Vu, Debashis Ghosh, Anand S. Mehta, Kristin Wallace, Alexander V. Alekseyenko

SpaceANOVA analyzes spatial co-occurrence of cell types in multiplex imaging data across tissue or disease groups using point process and functional ANOVA, revealing novel insights in colorectal cancer precursor lesions.

Journal of Proteome Research · Feb 28, 2024Peer-reviewedBioinformatics

Wd*-test: Robust Distance-Based Multivariate Analysis of Variance

Bashir ‎Hamidi, Kristin Wallace, Chenthamarakshan Vasu, Alexander V. Alekseyenko

The paper introduces a robust multivariate analysis of variance method for microbiome data that accounts for heteroscedasticity and unbalanced sample sizes.

Microbiome · Apr 1, 2019Peer-reviewedBioinformatics