Chenthamarakshan Vasu

CPAP/CENPJ is essential for the stability and function of ESCRT-pathway associated AAA+ ATPase VPS4B

This study shows CPAP stabilizes VPS4B protein and its localization to early endosomes, independent of its ESCRT-0 function, and reveals interactions critical for these processes.

Neutrophil Extracellular Trap Formation and Complement Activation Pathways Dominate Microbiota-dependent disease bias in lupus-prone female NZM2328 mice

This study shows that gut microbiota influences lupus-like disease outcomes differently in male and female NZM2328 mice, with females showing higher NET and complement pathway activation leading to disease susceptibility.

Centrosomal P4.1-associated protein (CPAP) is a novel regulator of ESCRT pathway function during endosome maturation

This paper identifies CPAP as a novel regulator of ESCRT pathway function during endosome maturation, showing its role in Rab5-to-Rab7 conversion and TSG101 recruitment to early endosomes.

Gut colonization by Bacteroides fragilis at juvenile age alters microbiota composition and accelerates type 1 diabetes progression in non-obese diabetic mice

This study shows that early-life colonization by Bacteroides fragilis in NOD mice accelerates type 1 diabetes progression by altering microbiota composition and immune responses.

Wd*-test: Robust Distance-Based Multivariate Analysis of Variance

The paper introduces a robust multivariate analysis of variance method for microbiome data that accounts for heteroscedasticity and unbalanced sample sizes.