Bingning Dong

LiverHomo integrates human liver scRNA-seq data with PPI and cell-cell communication networks to provide an interactive resource for exploring liver health and disease.

LiverDCP models disease biology by integrating single-cell data and protein interactions to identify disease-risk genes and therapeutic targets.

This study identifies a liver-to-atria inflammatory axis driven by osteopontin in MASH, leading to atrial remodeling and arrhythmia, with potential therapeutic targets.

This paper investigates 4-Methylumbelliferone's potential as a repurposed treatment for liver fibrosis, finding that it lacks efficacy at translatable doses and has an unclear mechanism.