Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewed
TrkA+ sensory neurons regulate osteosarcoma proliferation and vascularization to promote disease progression
Sowmya Ramesh, Qizhi Qin, Zhao Li…·Aaron Watkins James
This study shows that TrkA+ sensory neurons promote osteosarcoma progression by enhancing tumor growth, vascularization, and metastasis, and that inhibiting these neurons reduces disease severity and improves survival.
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