Author
Brigham and Women's HospitalORCID 0000-0002-4308-0974Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Woori Kim, Matthew R. Moll, Dandi Qiao…·Terri H. Beaty
This study investigates whether smoking modifies the effect of a polygenic risk score on reduced lung function, finding significant gene-by-smoking interactions in FEV1/FVC.
Richard J. Allen, Beatriz Guillén‐Guío, Justin M. Oldham…·Louise V. Wain
This study identifies three new genetic loci associated with idiopathic pulmonary fibrosis and confirms 11 previously reported ones, highlighting mTOR signaling and mitotic spindle-assembly genes in disease susceptibility.
Aabida Saferali, Jeong Hyun Yun, Margaret M. Parker…·COPDGene Investigators
The paper identifies FBXO38 as a novel COPD susceptibility gene by analyzing genetically driven alternative splicing and finding a protective exon associated with COPD risk.
Phuwanat Sakornsakolpat, Dmitry Prokopenko, Maxime Lamontagne…·Nicholas J. Wareham
This study expands the genetic landscape of COPD by identifying 82 risk loci, revealing associations with lung function, cell types, and comorbidities.
Nick R. G. Shrine, Anna L. Guyatt, Abdullah Mesut Erzurumluoglu…·Andrew P. Morris
The paper identifies 279 new genetic signals for lung function across multiple ancestries, showing associations with COPD and pleiotropic effects.
Maxime Lamontagne, Jean‐Christophe Bérubé, Ma’en Obeidat…·Yohan Bossé
The paper identifies 12 novel COPD loci and candidate causal genes using GWAS and lung eQTL data from 129 risk loci.