Andrea Hupfeld

Boosting reversible photocontrol of a photoxenase by an engineered conformational shift

This study enhances the reversible photocontrol of a photoxenase by engineering conformational shifts, achieving a light-regulation factor of ~100 with near-quantitative reversibility.

Expanding the Repertoire of Photoswitchable Unnatural Amino Acids for Enzyme Engineering

This study designs and synthesizes six new photoswitchable unnatural amino acids (psUAAs) for enzyme engineering, showing enhanced interaction potential and diverse photochemical behaviors.

Instantly Reversible Enzyme Regulation via Dichromatic Irradiation of Incorporated Azobenzene

The paper demonstrates a new method for reversible enzyme regulation using dichromatic irradiation of azobenzene, showing a two-fold increase in catalytic activity for one enzyme variant.