Direct RNA sequencing of the Escherichia coli epitranscriptome uncovers alterations under heat stress
Sebastián Riquelme-Barrios, Leonardo Vásquez-Camus, Siobhan A. Cusack, Korinna Burdack, Dimitar Plamenov Petrov, G. Nur Yeşiltaç, Stefanie Kaiser, Pascal Giehr, Kirsten Jung
This study uses direct RNA sequencing to analyze RNA modifications in E. coli under heat stress, revealing changes in m5C, m6A, and m6,6A levels in rRNA and shifts in mRNA modification patterns.
Nucleic Acids Research · Mar 3, 2025Peer-reviewedMicrobiology