David M. Leistner

This study shows that loss of KDM6A in hematopoietic cells impairs cardiac recovery after heart failure by causing epigenetic changes in myeloid cells that increase inflammation and worsen cardiac outcomes.

This study shows that gut microbial metabolite imidazole propionate impairs endothelial function and promotes atherosclerosis in both human and animal models.

The paper introduces MeTaQuaC, an open-source R package for quality control in targeted metabolomics, improving data reliability through systematic error detection and visualization.