Author

Alba Carreras

AstraZeneca (Sweden)ORCID 0000-0001-8787-8833Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Arash HaghikiaiD· 1 shared Barbara J. H. VerhaariD· 1 shared Christian WeberiD· 1 shared David M. LeistneriD· 1 shared Elisabeth Steinhagen‐ThiesseniD· 1 shared Elisabeth Tamara SträssleriD· 1 shared Frank SeeligeriD· 1 shared Fredrik BäckhediD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperSystems Biology

Arash HaghikiaORCID

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2 papers

Recent·Most cited

Systems BiologyArteriosclerosis Thrombosis and Vascular BiologyPeer-reviewedMar 27, 2025

Gut microbial metabolite imidazole propionate impairs endothelial cell function and promotes the development of atherosclerosis

Vanasa Nageswaran, Alba Carreras, Leander Reinshagen…·Arash Haghikia

This study shows that gut microbial metabolite imidazole propionate impairs endothelial function and promotes atherosclerosis in both human and animal models.

44 citationstop 1%

humanmouse

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Molecular BiologyNaturePeer-reviewedSep 1, 2018

In vivo CRISPR-Cas gene editing with no detectable genome-wide off-target mutations

Pınar Akçakaya, Maggie L. Bobbin, Jimmy A. Guo…·J. Keith Joung

The paper introduces VIVO, a method to detect off-target mutations from in vivo CRISPR-Cas editing, showing that well-designed gRNAs can edit efficiently without detectable off-targets.

322 citationstop 1%

humanCRISPR screen

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