Author

Joseph Silburt

University of TorontoORCID 0000-0002-4364-5277Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Isabelle AubertiD· 2 shared Alessia Apa· 1 shared Carol Janine SchuurmansiD· 1 shared Kate NoseworthyiD· 1 shared Kullervo HynyneniD· 1 shared Luis Fernando Rubio-Atonal· 1 shared Sheng-Kai Wu· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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2 shared papersNeuroscience

Isabelle AubertORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

NeuroscienceActa Neuropathologica CommunicationsPeer-reviewedJul 11, 2026

The Modulation of the Blood-Brain Barrier by Focused Ultrasound Stimulates Oligodendrogenesis

Kate Noseworthy, Joseph Silburt, Alessia Apa…·Isabelle Aubert

This study shows that focused ultrasound-mediated BBB modulation increases oligodendrogenesis by stimulating OPC proliferation in the hippocampus and striatum.

DOI 10.1186/s40478-026-02364-1

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintAug 17, 2020

MORPHIOUS: A Machine Learning Workflow to Naively Detect the Activation of Microglia and Astrocytes.

Joseph Silburt, Isabelle Aubert

MORPHIOUS uses unsupervised machine learning to detect activated microglia and astrocytes by comparing to non-activated glia, identifying novel activation features.

1 citation

mousespatial transcriptomics

𝕏 PostBluesky