Andries J. van Tonder

Phylodynamics and genome-wide association studies reveal the expansion of modern Streptococcus canis in Germany

This study analyzes 585 Streptococcus canis isolates to identify genetic factors driving its expansion, finding two dominant lineages associated with increased pathogenicity and host adaptation through genetic exchange with other streptococcal species.

Similarity of drug targets to human microbiome metaproteome promotes pharmacological promiscuity

The paper assesses similarity between drug targets and human microbiome metaproteomes to identify potential off-target effects and pharmacological promiscuity.

Nasopharyngeal competition dynamics are likely to be altered following vaccine introduction: bacteriocin prevalence and diversity among Icelandic and Kenyan pneumococci

The paper examines changes in bacteriocin prevalence and diversity in pneumococci from Iceland and Kenya before and after vaccine introduction, showing vaccine-induced shifts in bacterial population structure.

Inferring Mycobacterium bovis transmission between cattle and badgers using isolates from the Randomised Badger Culling Trial

The paper uses whole genome sequences and movement data to infer M. bovis transmission routes between cattle and badgers, finding higher cattle-to-cattle and badger-to-badger transmission rates than between species.

Population structure and transmission of Mycobacterium bovis in Ethiopia

This study uses whole genome sequencing to analyze the population structure and transmission patterns of Mycobacterium bovis in Ethiopia, identifying two distinct introductions of the Eu3 clonal complex from Europe.

Predicted structural mimicry of spike receptor-binding motifs from highly pathogenic human coronaviruses

The paper identifies potential structural mimicry of coronavirus spike receptor-binding motifs by human and non-human proteins using structural bioinformatics and docking simulations.

SeroBA: rapid high-throughput serotyping of Streptococcus pneumoniae from whole genome sequence data

SeroBA predicts Streptococcus pneumoniae serotypes from whole genome sequencing data with high concordance and scalability.

Genome sequencing reveals that Streptococcus pneumoniae possesses a large and diverse repertoire of antimicrobial toxins

The paper identifies 14 new bacteriocin gene clusters in Streptococcus pneumoniae genomes and shows their diversity and activity under stress and competition.

Heterogeneity Among Estimates Of The Core Genome And Pan-Genome In Different Pneumococcal Populations

The paper analyzes genome sequences of pneumococci from different populations to assess core and pan-genome variability, finding significant differences between Maela isolates and others.