Cholinergic forebrain activation improves cognition, boosts neurotrophin receptors, and lowers Aβ42 levels in the cerebral cortex of 5xFAD mice.
Jacob Kumro, Ashutosh Tripathi, Yun Lei, Jeremy Sword, Patrick M. Callahan, Alvin V. Terry, Xin‐Yun Lu, Sergei A. Kirov, Anilkumar Pillai, David T. Blake
This study shows that stimulating cholinergic pathways in 5xFAD mice improves cognition, increases neurotrophin receptors, and reduces Aβ42 levels in the cerebral cortex.
Cerebral Cortex · Feb 15, 2023Peer-reviewedNeuroscience