Elda Arrigoni

The paper maps the cellular taxonomy and circuit connectivity of the murine sublaterodorsal tegmental nucleus (SLD) using single-nucleus RNA sequencing, revealing a previously unknown pathway involved in REM sleep regulation.

This study identifies SCN Neuromedin-S neurons as regulators of arousal, sleep-wake cycles, and body temperature rhythms through circuit analysis and single-nuclei RNA-Seq.

This study maps the afferent projections to Calca/CGRP-expressing parabrachial neurons in mice using retrograde and anterograde tracing techniques, identifying GABAergic and glutamatergic inputs from multiple brain regions.

The paper identifies parabrachial CGRP neurons as regulators of awakenings to pain and shows their role in pain-induced sleep disturbances.

This study creates a spatially-resolved transcriptional atlas of the murine dorsal pons using snRNA-seq and MERFISH, identifying 120 neuronal subtypes and their spatial distribution.