Sathyajit Sai Bandaru

This paper investigates the combined effects of fentanyl and xylazine on respiratory and thermoregulatory function in mice, finding that their co-administration leads to prolonged respiratory depression and hypothermia through interactions between mu opioid and alpha2a adrenergic pathways.

This study identifies SCN Neuromedin-S neurons as regulators of arousal, sleep-wake cycles, and body temperature rhythms through circuit analysis and single-nuclei RNA-Seq.

The paper identifies parabrachial CGRP neurons as regulators of awakenings to pain and shows their role in pain-induced sleep disturbances.