Author

Askar Temirbek

University of Massachusetts Chan Medical SchoolORCID 0000-0002-4405-0283Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Andrés ColubriiD· 2 shared Fritz LekschasiD· 1 shared Kris SankaraniD· 1 shared Manuel G. GarberiD· 1 shared Olesea CojohariiD· 1 shared Timothy F. KowalikiD· 1 shared Yuming CaoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 13 mutual co-author links

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2 shared papersBioinformatics

Andrés ColubriORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintApr 23, 2026

scSketch: Interactive Sketch-based Trajectory Exploration and Pathway-Aware Analysis of Single-Cell Data

Askar Temirbek, Fritz Lekschas, Kris Sankaran, Andrés Colubri

scSketch allows interactive trajectory sketching and pathway-aware analysis of single-cell data, revealing infection-associated gradients in human oral keratinocytes.

DOI 10.64898/2026.04.16.718997

humanscRNA-seq

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Molecular BiologybioRxivPreprintSep 16, 2025

Human Cytomegalovirus Infection of Primary Human Oral Keratinocytes Induces Intermediate Keratinocyte Differentiation and an Altered Innate Immune Response

Olesea Cojohari, Yuming Cao, Askar Temirbek…·Timothy F. Kowalik

This study investigates HCMV infection in primary human oral keratinocytes, showing it drives dysregulated intermediate differentiation and alters immune responses to support viral replication.

1 citation

humanbulk RNA-seq

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