Long-term combination therapy with Metformin and Oxymetholone in a Fanconi Anemia mouse model
Craig Dorrell, A. Mack Peters, Qing‐Shuo Zhang, Niveditha Balaji, Kevin Baradar, Makiko Mochizuki‐Kashio, Angela M. Major, Milton J. Finegold, Chih‐Wei Liu, Kun Lü, Markus Grompe
This study evaluates the long-term combination therapy of metformin and oxymetholone in Fancd2-/- mice, finding no synergistic effect but improved HSC quiescence and partial gene expression normalization with metformin alone.
Pediatric Blood & Cancer · May 10, 2024Peer-reviewedGenetics