Author

Makiko Mochizuki‐Kashio

Oregon Health & Science UniversityORCID 0000-0001-9883-7260Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Markus GrompeiD· 2 shared A. Mack Peters· 1 shared Angela M. MajoriD· 1 shared Ayako Nakamura‐IshizuiD· 1 shared Ayano Yahagi· 1 shared Chih‐Wei LiuiD· 1 shared Craig DorrelliD· 1 shared Fumio Nakamura· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersGenetics

Markus GrompeORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Inflammatory restraint and membrane lipid integrity protect hematopoietic stem cells under stress

Ayano Yahagi, Haruka Okabe-Kitajima, Makiko Mochizuki‐Kashio, Kyoko Komai, Takayoshi Matsumura, Terumasa Umemoto, Mikiro Nawa, Fumio Nakamura, Takayuki Yoshimoto, Kohsuke Kanekura, Stephanie Zhi-Juan Xie, Keiyo Takubo, Toshio Suda, Ayako Nakamura‐Ishizu

This study shows that THPO protects HSCs from inflammatory stress by maintaining membrane lipid integrity and suppressing STAT1-driven pyroptosis.

bioRxiv · Aug 25, 2026 · PreprintCell Biology

Long-term combination therapy with Metformin and Oxymetholone in a Fanconi Anemia mouse model

Craig Dorrell, A. Mack Peters, Qing‐Shuo Zhang, Niveditha Balaji, Kevin Baradar, Makiko Mochizuki‐Kashio, Angela M. Major, Milton J. Finegold, Chih‐Wei Liu, Kun Lü, Markus Grompe

This study evaluates the long-term combination therapy of metformin and oxymetholone in Fancd2-/- mice, finding no synergistic effect but improved HSC quiescence and partial gene expression normalization with metformin alone.

Pediatric Blood & Cancer · May 10, 2024Peer-reviewedGenetics

FANCD2 Alleviates Physiologic Replication Stress in Fetal Liver HSC

Makiko Mochizuki‐Kashio, Young me Yoon, Theresa N Menna, Markus Grompe, Peter Kurre

This study shows FANCD2 reduces replication stress in fetal liver HSC, preventing excessive RPA-coated ssDNA and pChk1 activation.

bioRxiv · Sep 30, 2020 · PreprintDevelopmental Biology