Kun Lü

This study quantifies DNA adduct formation in mice exposed to ethylene oxide, showing dose-dependent differences between two adducts and their implications for cancer risk assessment.

This study investigates the dose-response relationship of ethylene oxide-induced genetic damage in mice to assess its potential carcinogenicity through a mutagenic mechanism.

This study shows that formaldehyde exposure alters histone methylation and acetylation in human cells, with changes resembling those in cancer and Alzheimer's disease.

This study shows that formaldehyde exposure increases Aβ40, Aβ42, and phosphorylated tau levels in 3D-cultured human neural cells, suggesting a role in Alzheimer's disease initiation and progression.

This study investigates sex-specific effects of gut microbiome on bile acid metabolism by transplanting feces from male and female mice and measuring bile acid profiles and gene expression.

This study evaluates the long-term combination therapy of metformin and oxymetholone in Fancd2-/- mice, finding no synergistic effect but improved HSC quiescence and partial gene expression normalization with metformin alone.

Adapterama II introduces a flexible and cost-effective method for amplicon sequencing on Illumina platforms using fusion primers and quadruple indexing.