PathologyPLoS PathogensPeer-reviewed
Highly accurate protein structure prediction-based virtual docking pipeline accelerating the identification of anti-schistosomal compounds
Wenjun Cheng, Mengjie Gu, Yuepeng Wang…·Jipeng Wang
This paper uses AlphaFold for protein structure prediction and virtual screening to identify anti-schistosomal compounds, finding seven active compounds including Carubicin hydrochloride, which targets U2AF65 and disrupts parasite splicing.
2 citations