Author

John C. Elfar

University of ArizonaORCID 0000-0002-4438-7118Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Prem Kumar GovindappaiD· 3 shared Govindaraj ElluriD· 2 shared Akash GuptaiD· 1 shared Amanda M. NelsoniD· 1 shared John P. HegartyiD· 1 shared Johnson V. JohniD· 1 shared Mark NobleiD· 1 shared Mashanipalya G. JagadeeshaprasadiD· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersNeuroscience

Prem Kumar GovindappaORCID

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3 papers

Recent·Most cited

NeuroscienceCell Death and DiseasePeer-reviewedJul 3, 2025

Erythropoietin decreases apoptosis and promotes Schwann cell repair and phagocytosis following nerve crush injury in mice

Prem Kumar Govindappa, Govindaraj Ellur, John P. Hegarty…·John C. Elfar

This study shows EPO reduces apoptosis and enhances Schwann cell repair and phagocytosis in mice with nerve crush injury, improving functional recovery.

3 citations

mousebulk RNA-seq

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BioengineeringbioRxivPreprintJun 5, 2025

Topical Delivery of 4-Aminopyridine Enhances Skin Regeneration in Burn Wounds

Govindaraj Ellur, Meenakshi Kamaraj, John C. Elfar…·Prem Kumar Govindappa

This study shows that topical 4-aminopyridine delivered via a gel formulation accelerates burn wound healing by enhancing re-epithelialization, hair follicle regeneration, and fibroblast to myofibroblast transformation.

1 citation

experimental assay

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NeurosciencebioRxivPreprintOct 31, 2021

4-aminopyridine promotes accelerated skin wound healing via neurogenic-mediator expression

Mashanipalya G. Jagadeeshaprasad, Prem Kumar Govindappa, Amanda M. Nelson…·John C. Elfar

This study shows that 4-aminopyridine accelerates skin wound healing by enhancing neurogenic mediator expression and promoting cellular interactions.

DOI 10.1101/2021.10.31.465317

humanexperimental assay

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