Novel Insights into Post-Myocardial Infarction Cardiac Remodeling through Algorithmic Detection of Cell-Type Composition Shifts
Brian Gural, Logan G. Kirkland, Abigail Hockett, Peyton B. Sandroni, Jiandong Zhang, Manuel Rosa‐Garrido, Samantha K. Swift, Douglas J. Chapski, Michael A. Flinn, Caitlin Claire O'Meara, Thomas M. Vondriska, Michaela Patterson, Brian C. Jensen, Christoph D. Rau
The paper develops an algorithm to correct cell-type composition in bulk RNAseq data, revealing novel gene pathways in post-myocardial infarction cardiac remodeling.
PLoS Genetics · Jul 24, 2025Peer-reviewedBioinformatics