Author

Lawrence C. Andrews

Ronin InstituteORCID 0000-0002-4451-1641Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:clustering· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Assay:protein structure· 1

Frequent Co-Authors

Alexei S. SoaresiD· 2 shared Herbert Jacob BernsteiniD· 2 shared Jean JakonciciD· 2 shared Robert M. SweetiD· 2 shared Babak AndiiD· 1 shared Dale F. KreitleriD· 1 shared Dieter K. SchneideriD· 1 shared Dima KozakoviD· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBioinformatics

Alexei S. SoaresORCID

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2 papers

Recent·Most cited

Serial Crystallography with Multi-stage Merging of 1000s of Images

Alexei S. Soares, Yusuke Yamada, Jean Jakoncic, Sean M. McSweeney, Robert M. Sweet, John Skinner, James Foadi, Martin R. Fuchs, Dieter K. Schneider, Wuxian Shi, Babak Andi, Lawrence C. Andrews, Herbert Jacob Bernstein

The paper introduces a multi-stage clustering strategy for serial crystallography data to improve dataset merging accuracy by first clustering based on unit cell parameters and then on reflection intensities.

bioRxiv · Jun 19, 2022 · PreprintBioinformatics

A simple technique to classify diffraction data from dynamic proteins according to individual polymorphs

Thu Nguyen, K.L. Phan, Dale F. Kreitler, Lawrence C. Andrews, Sandra B. Gabelli, Dima Kozakov, Jean Jakoncic, Robert M. Sweet, Alexei S. Soares, Herbert Jacob Bernstein

The paper introduces a multi-factor clustering method to classify diffraction data from dynamic proteins into polymorphs, using unit cell constants and intensities to cluster mixed-state data from chymotrypsinogen crystals.

Acta Crystallographica Section D Structural Biology · Feb 18, 2022Peer-reviewedMolecular Biology