NeuroscienceBrain CommunicationsPeer-reviewed
Midbrain organoids with an SNCA gene triplication model key features of synucleinopathy
Nguyen‐Vi Mohamed, Julien Sirois, Janani Ramamurthy…·Thomas M. Durcan
This study uses midbrain organoids from SNCA triplication patients to model synucleinopathy features, showing increased alpha-synuclein expression and aggregation linked to dopaminergic neuron loss.
88 citationstop 3%